(6-Fluoro-1H-indol-3-yl)acetic acid

(6-Fluoro-1H-indol-3-yl)acetic acid - Names and Identifiers

Name	6-Fluoroindole-3-acetic acid
Synonyms	6-F-IAA 6-FLUOROINDOLE-3-ACETIC ACID 6-Fluoroindole-3-acetic acid (6-Fluoroindol-3-yl)aceticacid 1H-Indole-3-aceticacid, 6-fluoro- 1-chloro-3-fluoro-2-methylbenzene 6-FLUOROINDOLE-3-ACETIC ACID(6FIAA) (6-Fluoro-1H-indol-3-yl)acetic acid 3-(Carboxymethyl)-6-fluoro-1H-indole 2-(6-fluoro-1H-indol-3-yl)acetic acid
CAS	443-75-4
EINECS	207-141-9
InChI	InChI=1/C7H6ClF/c1-5-6(8)3-2-4-7(5)9/h2-4H,1H3

(6-Fluoro-1H-indol-3-yl)acetic acid - Physico-chemical Properties

Molecular Formula	C10H8FNO2
Molar Mass	193.17
Density	1.446±0.06 g/cm3(Predicted)
Melting Point	159-163°C
Boling Point	417.9±30.0 °C(Predicted)
Flash Point	47.7°C
Vapor Presure	4.08mmHg at 25°C
pKa	4.38±0.30(Predicted)
Storage Condition	under inert gas (nitrogen or Argon) at 2-8°C
Refractive Index	1.502

(6-Fluoro-1H-indol-3-yl)acetic acid - Risk and Safety

Risk Codes	22 - Harmful if swallowed
Hazard Note	Irritant

(6-Fluoro-1H-indol-3-yl)acetic acid - Introduction

6-Fluoroindole-3-acetic acid is an organic compound with the chemical formula C10H8FNO2. The following is a description of its nature, use, preparation and safety information:

Nature:
6-Fluoroindole-3-acetic acid is a white crystalline powder with a special odor. It is stable at room temperature and can be dissolved in some organic solvents, such as ethanol and dimethyl sulfoxide. It is toxic to a certain extent and needs to be handled with caution.

Use:
6-Fluoroindole-3-acetic acid is widely used as an intermediate in organic synthesis in chemical research. It can be used to synthesize biologically active compounds, such as drugs, pesticides and bioactive agents. It can also be used for research in the field of agriculture and biotechnology.

Preparation Method:
The preparation method of 6-Fluoroindole-3-acetic acid can be obtained by the protonation and fluorination reaction of indole. Briefly, pyrrole and a fluorinating reagent are reacted under appropriate reaction conditions to produce 6-fluoroindole. Then, 6-Fluoroindole-3-acetic acid can be obtained by carboxylation reaction.

Safety Information:
6-Fluoroindole-3-acetic acid is a chemical and is subject to safe practices. It may be irritating to the eyes, skin and respiratory tract, so appropriate protective measures such as gloves, goggles and protective clothing should be taken when handling. At the same time, inhalation of the powder or contact with the skin should be avoided. In case of accidental contact, rinse immediately with plenty of water and seek medical help. During use and storage, please take care to comply with relevant regulations and guidelines.

Last Update：2024-04-09 21:11:58